Gene information
Official symbol DIO1
Official full name iodothyronine deiodinase 1
Gene type protein-coding gene
Chromosome1p32.3
Previous symbolTXDI1
Gene familySelenoproteins
Resources
Entrez Gene 1733
HGNC HGNC:2883
Ensembl ENSG00000211452
Vega OTTHUMG00000008435
UCSC uc021onq.2
GO terms: 7 records
GO Description Category LogP Number of genes Detail
GO:0006520 cellular amino acid metabolic process GO Biological Processes -2.20485551 9 More
GO:0006575 cellular modified amino acid metabolic process GO Biological Processes -7.43961662 26 More
GO:0010817 regulation of hormone levels GO Biological Processes -29.5190556 49 More
GO:0016491 oxidoreductase activity GO Molecular Functions -14.1519969 39 More
GO:0018958 phenol-containing compound metabolic process GO Biological Processes -4.03177682 7 More
GO:0042445 hormone metabolic process GO Biological Processes -9.53279610 17 More
GO:1901615 organic hydroxy compound metabolic process GO Biological Processes -22.7091625 41 More
KEGG pathways: 1 record
KEGG Description Category LogP Number of genes Detail
hsa04919 Thyroid hormone signaling pathway KEGG Pathway -4.89554233 17 More
Drug-Gene interaction
view
Related drugs: 1 record
Drug name Interaction type Source PMID View
propylthiouracil inhibitor ChemblInteractionsTTD view
Related studies: 2 records
Molecular factor Omics type Application Objective MI type Reference
NM_000792.7:c.*29C>T genomics free triiodothyronine[other] acute myocardial infarction Brozaitiene J et al. Genet Test Mol Biomarkers. 2018
NM_000792.7:c.*1058A>G genomics cardiovascular death[prognosis (bad)] acute myocardial infarction Kazukauskiene N et al. Sci Rep. 2020
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